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Research & Education At |
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SRBF Groups
Cytokines and Inflammation Group
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The Salford
Royal Biomedical Facility (SRBF) is located within new laboratories (November
2009) in the Sample preparation and storage The SRBF Biomedical
Repository holds several hundred thousand clinical research samples from
patients and other volunteers. These include tissues held under a licence
from the Human Tissue Authority. Cell and tissue function Patient cells and
tissues are investigated to understand how they function in health and
disease. These include leukocytes, endothelial, epithelial and connective
tissue cells, and a specialised facility for assessing gut tissue function ex
vivo. A number of human cell lines are also maintained to determine
effects of drugs and experimental materials as well as for bioassay. Histology The SRBF has a full
range of facilities for preparing and optically analysing fixed and frozen
tissue specimens, including image analysis. It specialises in
histopathological analysis of brain tissue. Molecular and genetic analysis The SRBF undertakes
a range of molecular diagnostic techniques for analysis of human genes and
proteins in clinical samples including single and multiplex immunoassay,
real-time PCR, chromatography and immunoblotting . The development and
standardisation of new assays and their clinical evaluation, particularly in
the analysis of biomarkers of inflammation and infection is a strength.
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